團隊簡介

學科帶頭人：商澎（教授 博導）

成員：楊鵬飛副教授  任麗副教授  呼延霆助理教授  呂歡歡助理教授  苑曦宸助理教授  韓煒博士后  楊建成博士后

團隊現(xiàn)有人員35人，其中教授1名，副教授2名，助理教授3名，博士后2名，在讀博士生14名，在讀碩士生13名，是一支年輕進取、富有活力的科研團隊。

聯(lián)系人：商澎，電話：029-88460391，E-mail：shangpeng@nwpu.edu.cn

研究方向

一、 空間及特殊環(huán)境生物學

1. 圍繞“骨質(zhì)流失”的生理現(xiàn)象，從機體整體、組織、細胞分子等多個層次，研究空間環(huán)境對肌肉骨骼系統(tǒng)的影響和作用機制，著重探討空間環(huán)境中的復合物理環(huán)境對骨骨源細胞結構功能的影響及作用機理；

2. 研究重力因素對擬南芥等植物的生物學效應及其機制；

二、 磁生物學

1. 研究組織及細胞的電磁特性；

2. 探討不同強度靜磁場（亞磁場、中等強度磁場及強磁場）調(diào)控細胞生理過程的作用機制；

三、 多尺度生物力學與力生物學

從超微觀、微觀及宏觀等多尺度、跨層次研究骨、關節(jié)及肌肉的力學性能及其響應外界力學環(huán)境的變化過程和生物力學機制。

近兩年代表性論文

1. Xu H, Ning D, Zhao D, Chen Y, Zhao D, Gu S, Jiang JX, Shang P*. Blockage of hemichannels alters gene expression in osteocytes in a high magneto-gravitational environment. Front Biosci (Landmark Ed). 2017, 22:783-794.

2. Xu H, Liu R, Ning D, Zhang J, Yang R, Riquelme MA, Li J, Jiang JX*, Shang P*. Biological Responses of Osteocytic Connexin 43 Hemichannels to Simulated Microgravity. J Orthepedic Res, 2016, 23224.

3. Ren Li, Wang Zhe, Huang Ling Wei, Yang PengFei, Shang Peng. Technologies for strain assessment from whole bone to mineralized osteoid level: a critical review. Journal of Mechanics in Medicine and Biology. 16: 1630002. 2016.

4. Li Chenrui, Wang Qian, Ren Tianjing, Zhang Yufeng, Christopher Wai Kei Lam, Moses S.S. Chow, Zuo Zhong. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. Journal of Pharmaceutical and Biomedical Analysis. 128: 286-293. 2016.

5. Li Ren, Peng-Fei Yang,Zhe Wang, Jian Zhang, Chong Ding, Peng Shang*. Biomechanical and biophysicalenvironment of bone from the macroscopic to the pericellular and molecularlevel. Journal of the Mechanical Behavior of Biomedical Materials,2015, 50, 104-122.

6. Ling-Wei Huang, Li Ren,Peng-Fei Yang, Peng Shang*. Response of osteoblasts to the stimulus of fluid flow.CriticalReview in Eukaryotic Gene Expression, 2015, 25(2): 153-162.

7. Peng-Fei Yang, AndreasKriechbaumer, Kirsten Albracht, Maximilian Sanno, Bergita Ganse, Timmo Koy,Peng Shang, Gert-Peter Brüggemann, Lars Peter Müller, J rn Rittweger*. On therelationship between tibia deformation and regional muscle contractions inhumans in vivo. Journal of Biomechanics,2015, 48(3): 456-464.

8. Yi Lv, Peng Shang*. Anilluminated growth system for the study of Arabidopsis thaliana duringdiamagnetic levitation by a superconducting magnet. Advance in Space Research, 2015, 55(1): 525-533.

9. Jian Zhang, Yong Zhao*,Peng Shang*. Responds of bone cells to microgravity: ground-based research, MicrogravityScience and Technology. 2015, 27(6): 455-464.

10. Hui Chen, Yong Zhao*,Peng Shang*. The distinctive sensitivity to microgravity of immune cell subpopulations,MicrogravityScience and Technology. 2015,27(6): 1-10.

11. Chong-Zhen Wang, PengShang*, Yong Zhao*. Microgravity activates p38 MAPK-C/EBPβ pathway to regulatethe expression of arginase and inflammatory cytokines in macrophages. InflammationResearch, 2015, 64: 301-311.

12. Yang Wang, Peng Shang*,Air-Rong Qian*. GeneChip expression profiling reveals the alterations of energymetabolism related genes in osteocytes under large gradient high magneticfields.PLoS One, 2015, 10(1):e0116359.

13. Li-Fang Hu, Peng Shang*.Mineralization initiation of MC3T3-E1 preosteoblast is suppressed undersimulated microgravity condition. Cell Biology International, 2015, 39(4): 364-372.

14. Hui-Yun Xu, Sumin Gu,Manuel A. Riquelme, Sirisha Burra, Danielle Callaway, Hong-Yun Cheng, TejaGuda, James Schmitz, Roberto J. Fajardo, Sherry L. Werner, Hong Zhao, PengShang, Mark L. Johnson, Lynda F. Bonewald, Jean X. Jiang*. Connexin 43 channelsare essential for normal bone structure and osteocyte viability.Journalof Bone and Mineral Research, 2015, 30(3): 436-448.

15. Yu-Long Sun, Zhi-Hao Chen,Xiao-Hu Chen, Chong Yin, Di-Jie Li, Xiao-Li Ma, Fan Zhao, Ge Zhang, Peng Shang,Ai-Rong Qian. Diamagnetic levitation promotes osteoclast differentiation fromRAW264.7 cells.IEEE Transactions on Biomedical Engineering, 2015, 62(3):900-8.

16. Yu-Long Sun, Xiaohu Chen,Zhihao Chen, Xiaoli Ma, Dijie Li, Peng Shang, Ai-Rong Qian*. Neuropeptide FFattenuates RANKL-induced differentiation of RAW264.7 cells into osteoclast-likecells. Archives of Oral Biology, 60:282-292, 2015.

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